Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1202097 | Journal of Chromatography A | 2012 | 14 Pages |
Abstract
⺠The possibilities of multi-column systems to cover a range of efficiencies are investigated. ⺠Serially-connected and parallel-connected column systems are compared. ⺠The serial connection mode offers a better compromise between average speed and total required column length than the parallel connection. ⺠The best possible serial connection system can get within 15-25% of the Knox & Saleem-speed limit at 1200 bar. ⺠The construction of wide-efficiency range systems is one of the application areas wherein the advantages of UHPLC-conditions will be most fully realized.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Deirdre Cabooter, Gert Desmet,