Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1203865 | Journal of Chromatography A | 2010 | 15 Pages |
Abstract
The review focuses on the role of ionic or ionisable single isomer derivatives (SIDs) of cyclodextrins on the separation of chiral analytes in capillary electrophoresis (CE), covering the period since the year 2000. The advantages of using pure compounds are discussed, as well as the ways to optimise the separations in the context of a rational approach to these techniques. Specific attention is paid to the modulation of the selector–analyte interaction. The advantage due to a detailed knowledge of equilibria occurring in solution during the CE run is underlined, particularly in the case of the presence of metal complexes, as occurs in chiral ligand exchange capillary electrophoresis (CLECE).
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Vincenzo Cucinotta, Annalinda Contino, Alessandro Giuffrida, Giuseppe Maccarrone, Marianna Messina,