| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1204714 | Journal of Chromatography A | 2009 | 17 Pages |
Abstract
High-temperature liquid chromatography (HTLC) is recognized today as a valuable technique in reversed-phase high-performance liquid chromatography (RP-HPLC). Column temperature can play a role in reducing analysis time, modifying retention, controlling selectivity, changing efficiency or improving detection sensitivity. The different effects of high temperatures on reversed-phase separations, the practical limitations due to the instrumentation, the limits and the main advantages of HTLC, especially for the separation of polar and ionized compounds, are reviewed.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sabine Heinisch, Jean-Louis Rocca,