| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1205401 | Journal of Chromatography A | 2008 | 8 Pages |
Abstract
Influence of column temperature and mobile phase composition (φ) on surface diffusion was studied in reversed-phase liquid chromatography using a C18-silica gel column and methanol–water mixtures. The temperature dependence of surface diffusion coefficient (Ds) was explained by considering that of the molecular diffusivity, suggesting the presence of a kind of correlation between surface and molecular diffusions. The influence of φ on Ds was accounted for by considering the restriction energy (Er) for surface diffusion. Physical meanings of the linear correlation between Er and the enthalpy change due to sample retention are discussed in connection with the mechanism of surface diffusion.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Kanji Miyabe,