Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1205565 | Journal of Chromatography A | 2008 | 9 Pages |
Abstract
To further extend our studies in the search for reversed phases with enhanced durability at high pH, zirconized silica has now been explored as an alternative support. The synthesis of the new stationary phases involves silanization of a zirconium-modified silica support with a C18 trifunctional silane, followed by endcapping. The chromatographic properties of the C18 phases based on zirconized silica are similar to their titanized silica counterparts. Accelerated high pH stability tests, using phosphate mobile phases and elevated temperature, have shown that the zirconized silica phases have promising advantages not only over similarly prepared non-metalized phases but also over titanized silica C18 phases.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
César R. Silva, Claudio Airoldi, Kenneth E. Collins, Carol H. Collins,