| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1205845 | Journal of Chromatography A | 2012 | 5 Pages |
Abstract
⺠Stability of a model pharmaceutical, fluoxetine, is probed in subcritical water. ⺠Remarkable stability in terms of time and temperature are observed. ⺠Some interference from starch excipient gelatinization is noted and characterized. ⺠Subcritical water can also extract fluoxetine from Prozac capsules quantitatively. ⺠Potential for subcritical water extraction as a viable method for pharmaceuticals.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jillian N. Murakami, Kevin B. Thurbide, Gordon Lambertus, Eric Jensen,