Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1206102 | Journal of Chromatography A | 2008 | 9 Pages |
Abstract
Mass spectrometry is often insufficient to distinguish between structural isomers, requiring confirmation using NMR spectroscopy. Here, a novel preparative technique based upon capillary multidimensional gas chromatography to isolate pure volatile components from complex samples is described. The method was developed through isolation of 1,4-dimethoxybenzene (5.2 μg, 10 injections) from a peppermint essential oil. Then isomers of 1- and 2-methylnaphthalene were isolated from a complex crude oil in sufficient amounts (3.1 μg, 38 injections and 5.0 μg, 35 injections) for discrimination using 1H NMR spectroscopy. This methodology is applicable to identify any volatile molecule in complex matrices requiring confirmation using NMR spectroscopy.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Graham T. Eyres, Sylvia Urban, Paul D. Morrison, Philip J. Marriott,