Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1206794 | Journal of Chromatography A | 2009 | 4 Pages |
Abstract
An alternative expression of the fundamental equation of multi-mode gradient elution involving simultaneous changes in mobile phase composition and flow rate is derived using simple kinetic arguments and graphic interpretation. The new expression consists of a system of two integral equations and provides an easy and direct way of predicting retention times under dual-mode gradient conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Kostas Papachristos, Panos Nikitas,