Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1207778 | Journal of Chromatography A | 2011 | 8 Pages |
Abstract
A new integrated 3-zone simulated moving bed (SMB) concept with internal racemization reaction was suggested recently for the production of single enantiomers from racemic mixtures [1] and [2]. The process utilizes an internal gradient to trigger the racemization within a single zone. It can deliver the pure enantiomer and outperforms conventional technologies. In this contribution, the concept is validated experimentally for the separation of a model system compound. The results demonstrate that the new concept is capable of producing a single enantiomer with purity, yield and conversion of 100%.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Javier García Palacios, Bernhard Kramer, Achim Kienle, Malte Kaspereit,