| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1208329 | Journal of Chromatography A | 2008 | 4 Pages |
Abstract
A method is described to enhance the sensitivity of fluorescence detection of cis-combretastatins using a short post-column photolysis coil with a mercury lamp, by inducing the rapid conversion to the trans isomer. Although all the compounds studied showed enhanced fluorescence after photolysis, there were large differences in the absolute level, with the inherent response of the catechol CA1 being much lower than the corresponding phenolic CA4. Brief exposure to the deuterium lamp in a photodiode array detector also resulted in significant enhancement.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Michael R.L. Stratford,