Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1208955 | Journal of Chromatography A | 2007 | 6 Pages |
Abstract
Stationary phase retention in a synchronous coil planet centrifuge or high-speed counter-current chromatography (CCC) relies on the interplay of hydrostatic (tangential and normal centrifugal) and hydrodynamic (Archimedean screw and mobile phase drag) forces. By offering a set of quantitative or semi-quantitative theoretical frameworks, this work has resolved fundamental questions such as “in the absence of mobile phase flow, how is the distribution of the two phases in a CCC column determined?” and “for Type-J CCC, do the helical and the spiral columns lead to similar performance?”
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Y.H. Guan, D. Fisher, I.A. Sutherland,