Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1209756 | Journal of Chromatography A | 2010 | 25 Pages |
Introduced in 1999 as a novel solventless sample preparation method, stir-bar sorptive extraction (SBSE) has become a popular analytical technique for the pre-concentration of organic compounds into a polydimethylsiloxane (PDMS)-coated stir-bar. In the last 10 years, hundreds of applications in the environmental, food and biomedical fields can be found in the literature. However, only PDMS-coated stir-bars are commercially available, which reduces the applicability of SBSE to the extraction of the non-polar compounds due to the poor extractability of more polar analytes. In this review, a view on method optimisation, limitations, potential solutions such as in-house coatings and derivatisation and novel applications in multi-residue analysis and passive sampling are revised.