Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1210401 | Journal of Chromatography A | 2006 | 7 Pages |
Abstract
Monolithic capillary columns containing native silica were modified by in situ coating with amylose tris(3,5-dimethylphenylcarbamate) and applied for enantioseparations in capillary liquid chromatography. Capillary columns were examined for 10 standard racemic compounds in order to compare the performance of monolithic silica columns with the common, 4.6 mm I.D. high-performance liquid chromatographic columns packed with particulate silica. The effects of polysaccharide coating and of the linear velocity of the mobile phase on peak performance were studied. Enantioseparations with an analysis time below 1 min were achieved for some chiral analytes.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bezhan Chankvetadze, Chiyo Yamamoto, Masami Kamigaito, Nobuo Tanaka, Kazuki Nakanishi, Yoshio Okamoto,