| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1213276 | Journal of Chromatography B | 2011 | 13 Pages |
Abstract
⺠We describe the application of DBS sampling and extraction to screen posaconazole in human whole blood. ⺠We demonstrate the advantages of our assay for potential use in therapeutic drug monitoring of sick patients. ⺠We examine the posaconazole DBS method's ruggedness and robustness by implementing guidelines commonly used in FDA regulated bioanalytical environments. ⺠Blood spot homogeneity was maintained and yielded accurate, precise and reproducible quantitation results.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Todime M. Reddy, Cristina I. Tama, Roger N. Hayes,