| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1214295 | Journal of Chromatography B | 2009 | 6 Pages |
Abstract
A new analytical method suitable for high throughput measurements of LTE4 in human urine is described. The methodology utilizes on-line enrichment and liquid chromatography/tandem mass spectrometry (LC/MS/MS). The novel LC/MS/MS method is rapid, linear from 5 to 500 pg/ml in spiked urine samples of both healthy and asthmatic subjects and more accurate and precise than enzyme immunoassay (EIA) and previous LC/MS/MS methods. Results from sample integrity experiments and preliminary values of urinary LTE4 from healthy adults and children are reported.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Michael Armstrong, Andrew H. Liu, Ronald Harbeck, Rick Reisdorph, Nathan Rabinovitch, Nichole Reisdorph,