Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1215539 | Journal of Chromatography B | 2007 | 7 Pages |
Abstract
The hexane and chloroform extracts of Derris scandens have displayed potent α-glucosidase inhibitory and moderate free radical scavenging activities. Phytochemical investigation of the active extracts led to the isolation of three new prenylated isoflavones, isoscandinone, scandenin A and scandenin B in addition to scandenone, scandinone and 4′, 5′, 7-trihydroxybiprenylisoflavone as the main constituents, having α-glucosidase enzyme inhibitory and free radical scavenging properties. A reversed-phase HPLC method is developed to quantify these active principles in the plant material, which can serve as an effective quality control method for standardization of D. scandens.
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Authors
Sridhar A. Rao, Pullela V. Srinivas, Ashok K. Tiwari, Uma Maheswara S. Vanka, Rama V. Subba Rao, Krishna R. Dasari, Madhusudana J. Rao,