Article ID Journal Published Year Pages File Type
1215539 Journal of Chromatography B 2007 7 Pages PDF
Abstract

The hexane and chloroform extracts of Derris scandens have displayed potent α-glucosidase inhibitory and moderate free radical scavenging activities. Phytochemical investigation of the active extracts led to the isolation of three new prenylated isoflavones, isoscandinone, scandenin A and scandenin B in addition to scandenone, scandinone and 4′, 5′, 7-trihydroxybiprenylisoflavone as the main constituents, having α-glucosidase enzyme inhibitory and free radical scavenging properties. A reversed-phase HPLC method is developed to quantify these active principles in the plant material, which can serve as an effective quality control method for standardization of D. scandens.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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