| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1221243 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 7 Pages |
Abstract
- A new impurity formed during heating of Artesunate tablets was detected by HPLC.
- Impurity B was identified as a 9,10-dehydrotetrahydrofuranyl acetate derivative.
- The same compound was alternatively prepared from anhydrodihydroartemisinin + FeII salt.
- 2-Deoxy-4α-hydroxy-9,10-anhydrodihydroartemisinin was also formed in this treatment.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Cedric Charrier, Gildas Bertho, Olivier Petigny, Philippe Moneton, Robert Azerad,