Article ID Journal Published Year Pages File Type
1221981 Journal of Pharmaceutical and Biomedical Analysis 2013 4 Pages PDF
Abstract

The chemical composition and antimicrobial activity studies on the essential oils of Hypericum rochelii Griseb. & Schenk and Hypericum umbellatum A. Kern. have been carried out for the first time. Seventy-nine compounds were identified in the essential oil of H. rochelii with n-nonane (24.7%), β-pinene (22.4%), germacrene D (7.5%), n-undecane (6.8%) and α-pinene (5.8%) as main constituents. One hundred and twenty-six compounds were identified in H. umbellatum essential oil with germacrene D (6.1%), (E)-nerolidol (4.4%), n-nonane (4.0%), (E)-caryophyllene (3.0%) and caryophyllene oxide (3.0%) as the most abundant components. Both oils were characterized by the presence of many components which could have numerous applications in food, pharmaceutical and perfume industries. Taxa studied herein belong to the section Drosocarpium Spach, and their intrasectional placement based on the essential oil profiles was discussed. The oils were tested in a broth microdilution assay against five bacterial and two fungal strains and found to have mainly moderate antimicrobial effects.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Composition of the volatiles isolated from two Hypericum taxa was evaluated. ► One hundred and forty-three constituents were identified in both oils. ► The antimicrobial activity was examined by microdilution method. ► We report chemical composition and antimicrobial activity for the first time.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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