Sensitive voltammetric determination of rutin at an in situ plated lead film electrode

A highly sensitive sensor for the determination of rutin by adsorptive stripping voltammetry was described. It consists of a lead film modified glassy carbon electrode (LF/GCE). In the proposed procedure rutin was accumulated by adsorption on the lead film electrode and then during the stripping step a lead film and the accumulated rutin were oxidised. The electrochemical behaviour of rutin at the lead film electrode was investigated by square-wave voltammetry. In the optimal conditions the anodic peak currents (measured by square-wave voltammetry) increased linearly with the concentration of rutin in the range of 5 × 10−10 to 1 × 10−8 mol L−1. The detection limit for rutin following 30 s of accumulation time was equal to 2.5 × 10−10 mol L−1. The method was successfully applied to the determination of rutin content in the tablets without previous separation.