| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1222811 | Journal of Pharmaceutical and Biomedical Analysis | 2008 | 7 Pages |
Abstract
A development of a rapid and sensitive LC–MS/MS method for the simultaneous detection of active ingredients of the euthanasic veterinarian drug Tanax® mixture is described.The method proposed, with a retention time of few minutes (6 min) was developed for an equine serum sample with solid-phase extraction (S.P.E). This S.P.E. procedure has been revealed useful for the determination of very low concentrations of Tanax® analytes (0.05–1 ng/ml).The method was validated in terms of specificity/selectivity, sensitivity, recovery and precision.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
M. Fidani, M.C. Gamberini, E. Pasello, F. Palazzoli, T. Dimasi, M. Montana,