| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1222818 | Journal of Pharmaceutical and Biomedical Analysis | 2008 | 4 Pages |
Abstract
This paper describes the development and validation of a HPLC-UV method (210 nm) for the simultaneous quantitation of artemether and lumefantrine in fixed dose combination tablets. The method showed to be linear (r2 > 0.99), precise (R.S.D. < 2.0%), accurate (recovery of 101.07% for artemether and 101.58% for lumefantrine), specific and robust. Four batches of artemether–lumefantrine tablets were assayed by the validated method. The artemether contents in the tablets varied from 98.61% to 103.35%, while lumefantrine contents were 97.92–100.48%.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Isabela da Costa César, Fernando Henrique Andrade Nogueira, Gérson Antônio Pianetti,