Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1223246 | Journal of Pharmaceutical and Biomedical Analysis | 2008 | 5 Pages |
Abstract
A sample labeled to be a natural herbal supplement for the enhancement of sexual function, was sent to Health Sciences Authority (HSA) of Singapore for testing. An unknown compound was detected and isolated from the product. The structure of the unknown compound was identified using LC-UV, high-resolution MS, ESI-MS/MS, IR, and NMR. The compound was characterized as a phosphodiesterase-5 (PDE-5) inhibitor, benzamidenafil. This is the first report of benzamidenafil, representing a new class of PDE-5 inhibitors, as an adulterant of a dietary supplement.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Peng Zou, Peiling Hou, Sharon Sze-Yin Oh, Xiaowei Ge, Bosco Chen Bloodworth, Min-Yong Low, Hwee-Ling Koh,