Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1223386 | Journal of Pharmaceutical and Biomedical Analysis | 2010 | 4 Pages |
Abstract
In the present work, we isolated two bioactive diterpenoids, horminone and 7-O-acetylhorminone and developed a micellar electrokinetic chromatography (MEKC) method for the simultaneous quantitative analysis of them in Turkish Salvia species. The optimal separation electrolyte was 50 mmol/L SDS and 25% methanol at pH 11.5. The limits of detection (S/N = 3) were 3.269 and 4.518 μg/mL for horminone and 7-O-acetylhorminone, respectively. The method has been applied successfully to analyze these two components in Salvia chionantha and Salvia kronenburgii acetone extracts.
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Authors
Nevin Öztekin, Selda Başkan, S. Evrim Kepekçi, F. Bedia Erim, Gülaçtı Topçu,