Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1223935 | Journal of Pharmaceutical and Biomedical Analysis | 2007 | 5 Pages |
Counterfeit and illegally manufactured drugs become a very important problem all over the world, hence, a search for new fast, easy, reliable and not expensive methods of drugs screening is essential. We describe the use of X-ray powder diffraction method for the fast screening of tablets for counterfeit medicines identification. The original Viagra® tablets and some counterfeit and/or imitations of Viagra were used as example. We demonstrate the application of diffraction method for discrimination of tablets coatings and for identification of differences in drug composition. The X-ray diffraction method turns out to be very fast and reliable for detecting counterfeits and imitation, and it correctly predicts the presence or absence of active substance and/or particular excipients.