Article ID Journal Published Year Pages File Type
1224132 Journal of Pharmaceutical and Biomedical Analysis 2008 6 Pages PDF
Abstract

Capillary zone electrophoresis (CZE) was developed for quantitative determination of hydroxycitric acid and hydroxycitric acid lactone in herbal products of Garcinia atroviridis Griff. Resolution optimization was investigated by varying type, concentration and pH of buffers. Using the pH 9.2 buffer containing 30 mM Na2B4O7, 90 mM NaH2PO4 and 0.5 mM tetradecyltrimethyl ammonium bromide, baseline resolution (Rs > 1.5) was found for all analytes. Advantages of the developed CZE method include simple sample preparation, fast analysis time within 5 min and high accuracy and precision.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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