Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1224933 | Journal of Pharmaceutical and Biomedical Analysis | 2006 | 7 Pages |
Abstract
Differential pulse polarographic (DPP) and square wave polarographic (SWP) techniques were applied at hanging mercury drop electrode (HMDE) for quantitative determination of tianeptine (TIA) in tablets. The adsorptive stripping voltammetric (ASV) behavior of TIA was also studied. TIA gave a sensitive reduction peaks at â1256, â1244 and â1072Â mV for DPP, SWP and ASV, respectively (versus Ag/AgCl) in Britton-Robinson buffer (B-R buffer) at pH 11. The solution conditions and instrumental parameters were optimized for the determination of TIA in tablets. Calibration plots and regression data validation, accuracy, precision, limit of detection, limit of quantitation and other aspects of analytical merit are presented.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Azza A. Gazy, Hoda Mahgoub, Essam F. Khamis, Rasha M. Youssef, M.A. El-Sayed,