Article ID Journal Published Year Pages File Type
1227531 Microchemical Journal 2016 11 Pages PDF
Abstract

•Immobilization strategies of aptamers.•Different target purification techniques.•Applications of AptaCapture assays.

Aptamers are widely used as diagnostic agents due to their specificity and high binding affinity to their cognate target. Apart from diagnostic applications, aptamers can also be employed to capture their cognate target. Aptamer-based capture (AptaCapture) assays enable capture of the target by the aptamers followed by target purification. This review focuses on the immobilization strategies of aptamers, different target purification techniques, and applications of AptaCapture assays.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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