| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1227547 | Microchemical Journal | 2016 | 6 Pages |
•Luminescent nanocrystal metal organic framework (NMOF1) has been used for biosensing of parathion.•The –COOH pendent group of organic linker on the surface of luminescent NMOF1 has been activated.•The fluorescent studies revealed successful interaction of anti-parathion antibody with parathion•Luminescent NMOF1 sensor allowed the detection of parathion in the range of 1 ppb to 1 ppm.•Developed biosensor is highly stable and sensitive for specific recognition of parathion.
The feasibility of the nanocrystal metal organic framework [Cd(atc)(H2O)2]n (NMOF1) as a biosensor is explored for the specific recognition of parathion. The luminescence properties of the NMOF1/antiparathion complex were tested for the detection of parathion. Because of the fluorescent properties, the anti-parathion antibody interacted with parathion in order to facilitate its detection at a dynamic concentration range from 1 ppb to 1 ppm. The assay was validated against some environmental samples by gas chromatography with solid phase extraction (SPE). Accordingly, the NMOF biosensor tested in this work is demonstrated as parathion-specific with high surface loading and high sensitivity.
