Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1228611 | Microchemical Journal | 2006 | 5 Pages |
Abstract
The preparation and electrochemical characterization of a carbon paste electrode modified with copper(II) hexacyanoferrate(III) (CuHCF) as well as its behavior as electrocatalyst toward the oxidation of N-acetylcysteine were investigated. The electrochemical behavior of the modified electrode and the electrooxidation of N-acetylcysteine were explored using sweep linear voltammetry. The best voltammetric response was observed for a paste composition of 20% (w/w) copper(II) hexacyanoferrate(III) complex, acetate buffer solution at pH of 6.0 as the electrolyte and scan rate of 10 mV sâ 1. A linear voltammetric response for N-acetylcysteine was obtained in the concentration range from 1.2 Ã 10â 4 to 8.3 Ã 10â 4 mol Lâ 1, with a detection limit of 6.3 Ã 10â 5 mol Lâ 1. The proposed electrode is useful for the quality control and routine analysis of N-acetylcysteine in pharmaceutical formulations.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Willian Toito Suarez, Luiz H. Jr., Orlando Fatibello-Filho,