| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1228759 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2016 | 5 Pages |
•A simple and efficient chemosensor HPIN is designed and synthesized.•The chemosensor has high selectivity and sensitivity for Al3 +.•It is a fluorescence “off–on” switch for Al3 +.•The coordination mode of HPIN with Al3 + is a 1:1 binding stoichiometry.•Potential utilization of HPIN as intracellular sensors of Al3 + was examined.
A simple and efficient fluorescent chemosensor for Al3 + is reported in the paper. The chemosensor is obtained by dehydration reaction of 2-hydroxy-1-naphthaldehyde and 2-aminophenol. The chemosensor has high selectivity and sensitivity for Al3 + and displays fluorescence “off–on” switch signal. The detection limit of the chemosensor for Al3 + can reach 1.0 × 10− 7 M in DMSO/H2O (1:9, v/v) solution. The mass spectra and Job's plot analysis confirm the 1:1 stoichiometry between chemosensor and Al3 +. Potential utilization of the probe as an intracellular sensor of Al3 + in human cancer (HiSa) cells is also examined by confocal fluorescence microscopy.
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