| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1229237 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2015 | 6 Pages |
•Synthesis of novel axially di-carboren substituted silicon phthalocyanine.•Carboren moiety and solvents effects on the photophysicochemical parameters of SiPc.•Singlet oxygen generation.•Photodynamic therapy properties.
The novel axially dicarborane substituted silicon (IV) (SiPc-DC) phthalocyanine was synthesized by treating silicon phthalocyanine dichloride SiPc(Cl)2 (SiPc) with o-Carborane monool. The compound was characterized by mass spectrometry, UV–Vis, FT-IR, 1H and 11B Nuclear Magnetic Resonance Spectroscopy (NMR). Spectral, photophysical (fluorescence quantum yield) and photochemical (singlet oxygen (ΦΔ) and photodegradation quantum yield (Φd)) properties of the complex were reported in different solutions (Dimethyl sulfoxide (DMSO), Dimethylformamide (DMF) and Toluene). The results of spectral measurements showed that both SiPc and carborane cage can have potential to be used as sensitizers in photodynamic therapy (PDT) and boron neutron capture therapy (BNCT) by their singlet oxygen efficiencies (ΦΔ = 0.41, 0.39).
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