| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1230270 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2014 | 4 Pages |
•Molecular recognition study of the drug molecule,carbamazepine.•Supramolecule p-t-butyl calix (8) arene was used as host molecule.•Thermodynamic property of the host-guest complexes formed has been studied.
The formation of inclusion complex of Carbamazepine, a antiseizure drug molecule, with the supra molecule, p-t-butyl calix(8)arene was studied. p-t-Butyl calix(8)arene was the host molecule and Carbamazepine was the guest molecule. Optical absorption spectral studies were carried out to study the molecular recognition properties of p-t-butyl calix(8)arene with Carbamazepine. The stochiometry of the host–guest complex and the binding constant were determined.
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