A novel chemiluminescence system with diperiodatonickelate (IV) for the determination of adrenaline

•A new chemiluminescence system with diperiodatonickelate.•The possible CL emission mechanism briefly discussed.•Successfully applied to the determination of adrenaline in pharmaceutical preparations.

A novel chemiluminescence (CL) system with diperiodatonickelate (IV) (DPN) was developed for the determination of adrenaline for the first time. The possible CL emission mechanism was briefly discussed by comparing the fluorescence emission spectra with CL spectra. Under the optimum conditions, the relative CL intensity was linear over the concentration of AD ranging from 1.0 × 10−7 to 1.0 × 10−5 g mL−1 with a detection limit of 4.0 × 10−8 g mL−1 (3σ). And the relative standard deviation was 3.7% for 2.0 × 10−6 g mL−1 AD (n = 11). The developed method has been successfully applied to the determination of AD in pharmaceutical preparations.

Graphical abstractIn this work, we report a new chemiluminescence (CL) reaction between adrenaline and diperiodatonickelate in alkaline medium. The possible CL emission mechanism was briefly discussed by comparing the fluorescence emission with CL spectra for the first time.Figure optionsDownload full-size imageDownload as PowerPoint slide