| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1230727 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2013 | 7 Pages |
•Probe L for Cu2+ was firstly synthesized based on ferrocenyl-1,3,4-thiadiazol.•Probe L was a multichannel chemosensor with electrochemical and optical properties.•Probe L was applied to monitor the intracellular Cu2+ level in Hela cells.
A novel probe based on ferrocenyl-1,3,4-thiadiazol-containing Schiff base was synthesized by the reaction of 5-ferrocenyl-1,3,4-thiadiazol-2-amine and 4-(diethylamino)salicylaldehyde, and characterized by IR, NMR, HRMS and X-ray analysis. UV–vis spectral and fluorescence property of the probe were investigated. The probe can be used to colorimetric sensitive and selective fluorescent recognition of Cu2+ in buffer solution. Moreover, the probe can detect Cu2+ by electrochemical method. Additionally, the Schiff base was successfully used as a selective and sensitive fluorescent probe for monitoring Cu2+ ions in living cells.
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