| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1230948 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2013 | 7 Pages |
Metal (II) complexes derived from S-benzyl-N-(1-ferrocenyl-3-(4-methylbenzene)acrylketone) dithiocarbazate; HL1, S-benzyl-N-(1-ferrocenyl-3-(4-chlorobenzene)acrylketone)dithiocarbazate; HL2, all the compounds were characterized using various spectroscopic techniques. The molar conductance data revealed that the chelates were non-electrolytes. IR spectra showed that the Schiff bases were coordinated to the metal ions in a bidentate manner with N, S donor sites. The ligands and their metal complexes have been screened for in vitro antibacterial, antifungal properties. The result of these studies have revealed that zinc (II) complexes 6 and 13 of both the ligands and copper (II) complexes 9 of the HL2 were observed to be the most active against all bacterial strains, antifungal activity was overall enhanced after complexation of the ligands.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Two novel Schiff bases and its fourteen metal (II) complexes were synthesized. ► The copper (II) complex 9 and zinc (II) complexes 6 and 13 were observed to be the best active against all bacterial strains. ► All metal (II) complexes exhibited better antifungal activity against corresponding ligands. ► The minimum inhibitory concentration (MIC) of zinc (II) complex 6 for Aspergillus niger was 1.319 × 10−8 M.
