| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1231605 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2015 | 6 Pages |
•The synergic effect of tanshinone I on killing cancer cells with curcumin was studied.•The excited energy level of tanshinone I was obtained by energy transfer reactions.•We obtained the molar absorption coefficient and rate constants for energy transfers.•The characteristic absorption spectra of 3Tan I∗ were recorded.
The excited triplet state of tanshinone I (Tan I) extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge was characterized by laser flash photolysis. The synergic effect of Tan I on the phototherapy of cancer cells with curcumin (Cur) was also investigated by MTT assay because the excited energy transfer from the triplet state of Tan I (3Tan I∗) to Cur occurred. At the same time, the characteristic absorption spectra of 3Tan I∗ were recorded, and its molar absorption coefficient and rate constants for several excited energy transfers were obtained. The photo-therapeutic effect of Cur is enhanced by combination with Tan I.
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