| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1233684 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2010 | 4 Pages |
Abstract
Secondary deuterium isotope effects (IE) on the acidity (pKa) of glycine were measured by 13C NMR titration. It was found that deuteration decreases the pKa by 0.034 ± 0.002. The experimental data are supported by theoretical calculations, which, in turn, allowed to relate the acidity decrease to the lowering of glycine vibrational frequencies upon deuteration.
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Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jonathan Romero, Andrés Reyes, Julien Wist,