Solvent-free synthesis, spectral correlations and antimicrobial activities of some aryl imines

A series of aryl imines have been synthesized by Fly-ash: H2SO4 catalyzed microwave assisted process under solvent-free conditions. The yields of the imines have been found to be more than 87%. The purity of all imines has been checked using their physical constants and spectral data as published earlier in literature. The UV λmaxCN(nm), infrared νCN(cm−1), NMR δ(ppm) of CH and CN spectral data have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied. The antimicrobial activities of All synthesised imines have been studied using Bauer–Kirby method.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► A series of aryl imines have been synthesized using green oxidative coupling of amines. ► Better yields of the imines (more than 85%) obtained. ► These aryl imines were characterized by their analytical and spectral data. ► Antimicrobial activities of these imines have been studied. ► Easy-workup procedure, environmentally solvent-free synthetic method was adopted.