Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1237091 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2009 | 4 Pages |
Abstract
Some acyl-thiourea derivatives containing isatin group were synthesized and their interactions with anions were investigated using UV-vis spectroscopy and 1H NMR titrations in DMSO and DMSO-d6, respectively. These compounds have a same molecular framework, functionalising with different groups lead to different anion binding strength of these receptors. Receptor 1 showed a higher binding affinity for AcOâ than for Fâ, due to the cooperative multiple hydrogen bond interactions of AcOâ with the acyl-thiourea group and N-H group in the indole unit of receptor 1. Displacing the N-H proton in the indole unit with -CH3 group, receptor 2 showed no obviously discriminative responses for Fâ, AcOâ and H2PO4â due to lack of such additional binding. In the case of receptor 3, which was functionalised with strong electron-withdrawing group, it showed selectively chromogenic response for Fâ based on double deprotonation of the receptor in DMSO, whereas AcOâ and H2PO4â induced single deprotonation only.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Shuzhen Hu, Yong Guo, Jian Xu, Shijun Shao,