Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1237163 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2005 | 4 Pages |
Abstract
HeI and HeII photoelectron spectra of 6-chloro-1,3-dimethyluracil have been measured. The assignment of the spectrum was made by comparison with photoelectron spectra of related compounds and by high-level OVGF calculations. The electronic structure changes in substituted nucleobases are discussed on the basis of photoelectron spectroscopic data. The electronic structure data are compared with structure-activity relationships regarding enzyme inhibition and complex formation. The electronic structure data give some insight into the nature of binding between nucleobases’ derivatives and different enzymes whose activity they inhibit.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Igor Novak, Branka Kovač,