| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1237485 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2009 | 5 Pages |
Abstract
A simple and sensitive label-free colorimetric detection of telomere DNA has been developed. It was based on the color change of gold nanoparticles (AuNPs) due to DNA hybridization. UV–vis spectra and transmission electron microscopy (TEM) were used to investigate the change of AuNPs. Under the optimized conditions, the linear range for determination of telomere DNA was 5.7 × 10−13 to 4.5 × 10−6 mol/L. The detection limit (3σ) of this method has decreased to pico-molar level.
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Authors
Yingying Qi, Li Li, Baoxin Li,