| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1237566 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2008 | 4 Pages |
Abstract
A series of β-phenyl-2-isoxazolidineethanols having cis-disposed substituents at C(4) and C(5) has been prepared by asymmetric nitrone cycloaddition reactions and their NMR spectra recorded over a wide range of temperatures. The spectra in CDCl3 at low temperatures indicate the presence of two interconverting invertomers for some of the tri-substituted isoxazolidines. The effect of H-bonding - intramolecular in CDCl3 and intermolecular in CD3OD - on the population ratio of the nitrogen invertomers has been investigated. The nitrogen inversion barriers are determined using complete line-shape analysis, and their dependence on solvent is discussed.
Keywords
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Shaikh A. Ali, Mohamed I.M. Wazeer,