| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1238079 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | 2007 | 5 Pages |
Abstract
The interaction of cloxacillin sodium with β-cyclodextrin (β-CD) has been studied by several analytical techniques, including 1H NMR, fluorescence spectroscopy, infrared spectroscopy. In this paper, solid inclusion complex of cloxacillin sodium with β-CD was synthesized by the coprecipitation method. In addition, the characterization of the inclusion complex has been proved by fluorimetry, infrared spectroscopy and 1D, 2D NMR. The experimental results confirmed the existence of 1:1 inclusion complex of cloxacillin sodium with β-CD. The formation constant of complex was determined by fluorescence method and 1H NMR. Spacial configuration of complex has been proposed on 2D NMR technique.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jian-Bin Chao, Bing-Tai Zhang,