Article ID Journal Published Year Pages File Type
1238144 Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2008 6 Pages PDF
Abstract

1-Cyclohexyl-3-tosylurea (HL) and its two complexes, ML2·2H2O [MNi(1), and Cd(2)], have been synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra and thermal analyses. In addition, the DNA-binding properties of the ligand and the two complexes have been investigated by electronic absorption, fluorescence, CD spectroscopy and viscosity measurements. The experiment results suggest that the ligand and its two complexes bind to DNA via a groove binding mode, and the binding affinity of the complex 2 is higher than that of the complex 1 and the ligand.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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