Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1242408 | Talanta | 2016 | 7 Pages |
•Water-soluble Gd-doped CdTe QDs were successfully synthesized by a one-step strategy.•The photoluminescence quantum yield of the prepared Gd:CdTe QDs was up to 42.5%.•Their function as a fluorescence-MRI dual model agent was illustrated.•The Gd:CdTe QDs have good biocompatibility and great potential for biomedical application.
A facile one-pot strategy has been developed for the aqueous synthesis of Gd doped CdTe (Gd:CdTe) QDs as fluorescence and magnetic resonance imaging dual-modal agent. The prepared Gd:CdTe QDs showed narrow size distribution and the average size was less than 5 nm. The amount of Gd3+ dopant in Gd:CdTe QDs significantly affected the optical properties of obtained QDs. The highest PL QY for the prepared Gd:CdTe QDs was up to 42.5%. The QDs showed the weak toxicity and significant enhancement in MRI signal. The specific relaxivity value (r1) was determined to be 4.22 mM−1s−1. These properties make the prepared Gd:CdTe QDs be an effective dual-modal imaging agent and have great potential applications in biomedical field.
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