Article ID Journal Published Year Pages File Type
1243095 Talanta 2008 4 Pages PDF
Abstract
The proposed methodology allowed the determination of mannitol concentrations between 25 mmol L−1 and 1 mol L−1, with good precision (R.S.D. < 4.7%, n = 3) and a sampling frequency of about 60 h−1. The procedure was applied to the determination of mannitol in pharmaceuticals and in human urine samples without any pretreatment process. The results obtained for pharmaceutical formulations were statistically comparable to those provided by the reference method (R.D. < 4.6%); recoveries values obtained in the analysis of spiked urine samples (between 94.9 and 105.3% of the added amount) were also satisfactory.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, , , ,