Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1243494 | Talanta | 2010 | 7 Pages |
Abstract
Based on combination of chiral recognition ability of β-cyclodextrin (β-CD) derivatives and flexibility of monolithic material, a series of chiral stationary phases (CSPs) were prepared by the immobilization of β-CD and three of its derivatives to the epoxy-activated poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolith under mild condition. Immobilization condition for the connection reaction by different functional groups and bonding ways was studied to obtain good enantiomer selectivity. Prepared CSPs were evaluated by separating racemic mixtures of eight amino acids and two chiral drugs with capillary electrochromatography (CEC).
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Yingjie Li, Chunhui Song, Lingyi Zhang, Weibing Zhang, Honggang Fu,