Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1243674 | Talanta | 2009 | 4 Pages |
Abstract
Gold nanoparticles (AuNPs) were assembled on the surface of polystyrene (PS) and polyaniline (PANI) core–shell nanocomposite (PS@PANI) for the immobilization of HL-60 leukemia cells to fabricate a cell electrochemical sensor. The immobilized cells exhibited irreversible voltammetric response and increased the electron transfer resistance with a good correlation to the logarithmic value of concentration ranging from 1.6 × 103 to 1.6 × 108 cells mL−1 with a limit of detection of 7.3 × 102 cells mL−1 at 10σ. This biosensor was simple, low cost and disposable, which implied that the PS@PANI/Au composites can regard as the potential applications for clinical applications.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Miaomiao Gu, Jingjing Zhang, Ye Li, Liping Jiang, Jun-Jie Zhu,