Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1244674 | Talanta | 2010 | 5 Pages |
Abstract
A sensitive biosensor with supramolecular architecture was designed and implemented here to detect choline. Choline oxidase and horseradish peroxidase were assembled onto the polymer of thiolated β-cyclodextrin and platinum nanoparticles modified gold electrode through 1-adamantane carboxylic acid coupling. Square wave voltammetry showed that the reduction currents at 0.38 mV had a linear relationship with the logarithms of choline concentrations in the range of 10−9–10−2 M, and the detection limit was down to 0.1 nM. Such biosensor also exhibited excellent selectivity, reproducibility and stability.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Zhanxia Zhang, Juan Wang, Xiaolei Wang, Yong Wang, Xiurong Yang,