Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1244693 | Talanta | 2010 | 5 Pages |
Abstract
A system device using multifunctional conjugated copolymer poly(5-hydroxy-1,4-naphthoquinone-co-hydroxy-2-thioacetic acid-1,4-naphthoquinone) acting both as immobilizing and transducing element for reagentless immunosensor has been constructed. Its functionality was evaluated in an antigen-antibody interaction model using ovalbumin-anti-ovalbumin. It was shown that the system specifically detects via electrochemical signal the antigen-antibody immune interaction in a reagentless context. Comparison to the conventional ELISA technique relevant to performance and sensitivity was presented.
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Authors
B. Piro, Q.D. Zhang, S. Reisberg, V. Noel, L.A. Dang, H.T. Duc, M.C. Pham,